Autism as an adaptive common variant pathway for human brain development.

Citation data:

Developmental cognitive neuroscience, ISSN: 1878-9307, Vol: 25, Page: 5-11

Publication Year:
2017
Usage 452
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PMID:
28233663
DOI:
10.1016/j.dcn.2017.02.004
Author(s):
Johnson, Mark H
Publisher(s):
Elsevier BV
Tags:
Neuroscience
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review description
While research on focal perinatal lesions has provided evidence for recovery of function, much less is known about processes of brain adaptation resulting from mild but widespread disturbances to neural processing over the early years (such as alterations in synaptic efficiency). Rather than being viewed as a direct behavioral consequence of life-long neural dysfunction, I propose that autism is best viewed as the end result of engaging adaptive processes during a sensitive period. From this perspective, autism is not appropriately described as a disorder of neurodevelopment, but rather as an adaptive common variant pathway of human functional brain development.