Patients with hepatocellular carcinoma and hepatitis C were less likely to achieve sustained virologic response while receiving direct-ac...
Hepatocellular carcinoma decreases the chance of successful hepatitis C virus therapy with direct-acting antivirals.
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Journal of hepatology, ISSN: 1600-0641, Vol: 66, Issue: 6, Page: 1173-1181
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The approval of all-oral direct-acting antiviral (DAA) regimens for the treatment of hepatitis C virus (HCV) has led to the expansion of therapy to include patients with cirrhosis who have hepatocellular carcinoma (HCC). Data on the use of DAAs in HCV+ patients with HCC is limited. The aim of this study was to assess the efficacy of all-oral-DAA regimens in HCV+ cirrhotic patients who have or had HCC compared to those without HCC.