Plant latex capped colloidal silver nanoparticles: A potent anti-biofilm and fungicidal formulation

Citation data:

Journal of Molecular Liquids, ISSN: 0167-7322, Vol: 230, Page: 705-713

Publication Year:
2017
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DOI:
10.1016/j.molliq.2017.01.004
Author(s):
Santosh Kumar; Wriddhee Bhattacharya; Mukesh Singh; Dipankar Halder; Atanu Mitra
Publisher(s):
Elsevier BV
Tags:
Materials Science; Physics and Astronomy; Chemistry
article description
We report a completely green, cheap and convenient route for the fabrication of highly stable silver nanocolloid from aqueous silver nitrate using latex of two different plant Jatropha curcas and Lannea grandis. The existence of silver nanoparticle has been proved by UV–Vis spectroscopy, electron diffraction and energy dispersive X-ray (EDX) analysis. The transmission electron microscopy (TEM) images show relatively higher polydispersity with average diameter 47.0 ± 2.0 nm of nanoparticle synthesized by latex of J. curcas where as latex of L. grandis generated highly monodisperse spherical particle having average diameter 7.6 ± 0.5 nm. The Fourier transform infrared (FTIR) spectra and HRTEM image demonstrate that the components of latex interacted with the surface of silver nanoparticle to make a thin layer of coating on the metal. The as-synthesized silver nanocolloid is a highly stable dispersion which exhibited no precipitation even after one year of storage. The cyto-toxicity of the nanocolloid has been tested out by hemolytic study of goat red blood corpuscles. Furthermore, we also tested the antifungal activity of this low-cytotoxic silver nanocolloid against plankotonic cell as well as biofilm of Candida albicans by spectrophotometric and microscopic (light microscopy and scanning electron microscopy) analysis. Our finding demonstrates that the bio-fabricated silver nanocolloid can be used as promising nano-drug formulation to combat against fungal infections.