Modulation of vascular function and anti-aggregation effect induced by (1→3) (1→6)-β-d-glucan of Saccharomyces cerevisiae and its carboxymethylated derivative in rats.

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Pharmacological reports : PR, ISSN: 1734-1140, Vol: 69, Issue: 3, Page: 448-455

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Bezerra, Lorena Soares; Magnani, Marciane; Castro-Gomez, Raul Jorge Hernan; Cavalcante, Hassler Clementino; Silva, Tays Amanda Felisberto da; Vieira, Renata Layne Paixão; Medeiros, Isac Almeida de; Veras, Robson Cavalcante
Elsevier BV
Pharmacology, Toxicology and Pharmaceutics
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article description
β-d-Glucans are polysaccharides found in the cell walls of yeasts, such as Saccharomyces cerevisiae, and they have been studied because of their beneficial effects on health, mainly in terms of immunomodulation. However, information on the action of these polymers on vascular and platelet function is still scarce. This study evaluate the effect of (1→3) (1→6) β-d-glucan (βG-Sc) and its carboxymethylated derivative (CM-G) on vascular and platelet function in rats.