World's longest surviving liver-pancreas recipient.

Citation data:

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, ISSN: 1527-6465, Vol: 13, Issue: 7, Page: 957-60

Publication Year:
2007
Usage 244
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Repository URL:
http://d-scholarship.pitt.edu/id/eprint/5619
PMID:
17600350
DOI:
10.1002/lt.21223
Pitt D-Scholarship Id:
5619
PMCID:
PMC2994251
Author(s):
Harary, Albert M; Abu-Elmagd, Kareem; Thai, Ngoc; Shapiro, Ron; Todo, Satoru; Fung, John J; Starzl, Thomas E
Publisher(s):
Wiley-Blackwell
Tags:
Medicine
article description
In July 1988, the liver and pancreas of a cadaveric donor were transplanted separately into a man with type 1 diabetes with end-stage chronic hepatitis B virus. Two features of the operation may help explain the patient's current status as the longest-lived liver-pancreas recipient. One was enteric drainage of pancreatic exocrine secretions. The other was delivery of the pancreas venous effluent to the host portal system and then directly to the hepatic allograft.