Duplicate item. See http://hdl.handle.net/1969.1/ETD-TAMU-2074

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West Nile Virus; Spatial Epidemiology
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West Nile Virus (WNV) first appeared in Texas equids during June 2002. It has since spread rapidly across the state and apparently become endemic. Data from outbreaks occurring between 2002 and 2004 were analyzed to determine hotspots of equine WNV disease, identify environmental factors associated with outbreaks, and to create risk maps of locations with horses at a higher risk of the disease. Kriging was used to model the smoothed WNV attack rates, and interpolated rates were mapped to describe the spatial distribution of WNV disease risk in Texas. A retrospective time-space analysis using a Poisson model was conducted on each year's data to identify clusters with high attack rates. The resulting overlapping yearly clusters were considered areas of hyperendemicity (hotspots). The counties identified as hotspots included Hockley, Lubbock, and Lynn (primary cluster) and Leon and Roberstson (secondary cluster). Environmental and geographic features were added to the disease maps and analyzed to determine possible environmental factors associated with outbreaks. Locations in close proximity to lakes, bird breeding routes, migratory flyway zones, crop farm and agricultural land, and all dense vegetation were found to be important environmental predictors. Finally, risk maps were created that combined surveillance data on WNV positive mosquito collections and wild bird WNV cases with previously identified environmental risk factors to predict areas of high occurrence of WNV. These risk maps could be used to implement various preventative measures to reduce the transmission of WNV in the Texas equine industry.