Evolutionary Chance Mutation: A Defense of the Modern Synthesis' Consensus View

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Philosophy and Theory in Biology, ISSN: 1949-0739, Vol: 2, Issue: 20170609, Page: 1-22

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Merlin, Francesca
University of Michigan Library, Michigan Publishing, University of Michigan Library
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One central tenet of the Modern Evolutionary Synthesis (1930s-1950s), and the consensus view among biologists until now, is that all genetic mutations occur by “chance” or at “random” with respect to adaptation. However, the discovery of some molecular mechanisms enhancing mutation rate in response to environmental conditions has given rise to discussions among biologists, historians and philosophers of biology about the “chance” vs “directed” character of mutations (1980s-2000s). In fact, some argue that mutations due to a particular kind of mutator mechanisms challenge the Modern Synthesis because they are produced when and where needed by the organisms concerned. This paper provides a defense of the Modern Synthesis’ consensus view about the chance nature of all genetic mutations by reacting to Jablonka and Lamb’s analysis of genetic mutations (2005) and the explicit Lamarckian flavor of their arguments. I argue that biologists can continue to talk about chance mutations according to what I call and define as the notion of “evolutionary chance,” which I claim is the Modern Synthesis’ consensus view and a reformulation of Darwin’s most influential idea of “chance” variation. Advances in molecular genetics are therefore significant but not revolutionary with respect to the Modern Synthesis’ paradigm.

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Extended evolutionary synthesis

The extended evolutionary synthesis is a set of extensions of the earlier modern synthesis of evolutionary biology that took place between 1918 and 1942. The extended evolutionary synthesis was called for in the 1950s by C. H. Waddington, argued for on the basis of punctuated ...

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Teleonomy is the quality of apparent purposefulness and of goal-directedness of structures and functions in living organisms brought about by natural laws (like natural selection). The term derives from two Greek words, τέλος telos ("end, purpose") and νόμος nomos ("law"), and...

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