Validating Animal Models

Citation data:

THEORIA. An International Journal for Theory, History and Foundations of Science, ISSN: 0495-4548, Vol: 30, Issue: 2, Page: 163-181

Publication Year:
2015
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Repository URL:
http://philsci-archive.pitt.edu/id/eprint/12145
DOI:
10.1387/theoria.12761
Author(s):
Nina A. Atanasova
Publisher(s):
UPV/EHU Press, Euskal Herriko Unibertsitatea / Universidad del PaĆ­s Vasco
Tags:
Arts and Humanities
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article description
This paper responds to a recent challenge for the validity of extrapolation of neurobiological knowledge from laboratory animals to humans. According to this challenge, experimental neurobiology, and thus neuroscience, is in a state of crisis because the knowledge produced in different laboratories hardly generalizes from one laboratory to another. Presumably, this is so because neurobiological laboratories use simplified animal models of human conditions that differ across laboratories. By contrast, I argue that maintaining a multiplicity of experimental protocols and simple models is well justified. It fosters rather than precludes the validity of extrapolation of neurobiological knowledge. The discipline is thriving.

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