Henrin A: A New Anti-HIV Ent-Kaurane Diterpene from Pteris henryi.

Citation data:

International journal of molecular sciences, ISSN: 1422-0067, Vol: 16, Issue: 11, Page: 27978-87

Publication Year:
2015
Usage 36
Abstract Views 29
Full Text Views 6
Link-outs 1
Social Media 1
Tweets 1
Citations 5
Citation Indexes 5
Repository URL:
https://repository.hkbu.edu.hk/scmd_ja/62
PMID:
26610490
DOI:
10.3390/ijms161126071
PMCID:
PMC4661929
Author(s):
Li, Wan-Fei, Wang, Juan, Zhang, Jing-Jie, Song, Xun, Ku, Chuen-Fai, Zou, Juan, Li, Ji-Xin, Rong, Li-Jun, Pan, Lu-Tai, Zhang, Hong-Jie
Publisher(s):
MDPI AG, MDPI
Tags:
Chemical Engineering, Biochemistry, Genetics and Molecular Biology, Chemistry, Computer Science, Anti-HIV activity, Bioactivity evaluation, Ent-kaurane diterpene, Henrin A, Pteris henryi
Most Recent Tweet View All Tweets
article description
Henrin A (1), a new ent-kaurane diterpene, was isolated from the leaves of Pteris henryi. The chemical structure was elucidated by analysis of the spectroscopic data including one-dimensional (1D) and two-dimensional (2D) NMR spectra, and was further confirmed by X-ray crystallographic analysis. The compound was evaluated for its biological activities against a panel of cancer cell lines, dental bacterial biofilm formation, and HIV. It displayed anti-HIV potential with an IC50 value of 9.1 µM (SI = 12.2).

This article has 0 Wikipedia mention.