Anxiety and behavioural disturbance as markers of prodromal Alzheimer's disease in patients with mild cognitive impairment.

Citation data:

International journal of geriatric psychiatry, ISSN: 1099-1166, Vol: 26, Issue: 2, Page: 166-72

Publication Year:
2011
Usage 2514
Abstract Views 1968
Full Text Views 514
Link-outs 20
Downloads 12
Captures 305
Exports-Saves 254
Readers 51
Citations 43
Citation Indexes 43
Repository URL:
http://hdl.handle.net/10147/129395
PMID:
21229599
DOI:
10.1002/gps.2509
Author(s):
Gallagher, Damien; Coen, Robert; Kilroy, Dana; Belinski, Kate; Bruce, Irene; Coakley, Davis; Walsh, Bernard; Cunningham, Conal; Lawlor, Brian A
Publisher(s):
Wiley-Blackwell
Tags:
Medicine
article description
Depression and anxiety have been reported to be independently predictive of conversion to Alzheimer's disease (AD) in patients with mild cognitive impairment (MCI). Anxiety symptoms have been less well studied and findings in this regard have been inconsistent. The objectives of this study are to determine which symptoms among a range of neuropsychiatric symptoms known to commonly occur in patients with MCI are predictive of later conversion to AD. We also wish to determine whether these symptoms track existing measures of declining cognitive and functional status or may be considered distinct and sensitive biomarkers of evolving Alzheimer's pathology.