Unraveling Mycobacterium tuberculosis genomic diversity and evolution in Lisbon, Portugal, a highly drug resistant setting.
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BMC genomics, ISSN: 1471-2164, Vol: 15, Issue: 1, Page: 991
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- Biochemistry, Genetics and Molecular Biology; Whole genome sequencing; MDR-TB; XDR-TB; Lisboa family; Microevolution
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Multidrug- (MDR) and extensively drug resistant (XDR) tuberculosis (TB) presents a challenge to disease control and elimination goals. In Lisbon, Portugal, specific and successful XDR-TB strains have been found in circulation for almost two decades.