Unraveling Mycobacterium tuberculosis genomic diversity and evolution in Lisbon, Portugal, a highly drug resistant setting.

Citation data:

BMC genomics, ISSN: 1471-2164, Vol: 15, Issue: 1, Page: 991

Publication Year:
2014
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Repository URL:
http://hdl.handle.net/10754/337670
PMID:
25407810
DOI:
10.1186/1471-2164-15-991
PMCID:
PMC4289236
Author(s):
Perdigão, João; Silva, Hugo; Machado, Diana; Macedo, Rita; Maltez, Fernando; Silva, Carla; Jordao, Luisa; Couto, Isabel; Mallard, Kim; Coll, Francesc; Hill-Cawthorne, Grant A.; McNerney, Ruth; Pain, Arnab; Clark, Taane G; Viveiros, Miguel; Portugal, Isabel Show More Hide
Publisher(s):
Springer Nature
Tags:
Biochemistry, Genetics and Molecular Biology; Whole genome sequencing; MDR-TB; XDR-TB; Lisboa family; Microevolution
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article description
Multidrug- (MDR) and extensively drug resistant (XDR) tuberculosis (TB) presents a challenge to disease control and elimination goals. In Lisbon, Portugal, specific and successful XDR-TB strains have been found in circulation for almost two decades.