TiPs: a database of therapeutic targets in pathogens and associated tools.

Citation data:

Bioinformatics (Oxford, England), ISSN: 1367-4811, Vol: 29, Issue: 14, Page: 1821-2

Publication Year:
2013
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Repository URL:
http://hdl.handle.net/10754/596827
PMID:
23698860
DOI:
10.1093/bioinformatics/btt289
PMCID:
PMC3702258
Author(s):
Lepore, Rosalba; Tramontano, Anna; Via, Allegra
Publisher(s):
Oxford University Press (OUP)
Tags:
Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics; Medicine; Drug Discovery; Databases, Pharmaceutical
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article description
The need for new drugs and new targets is particularly compelling in an era that is witnessing an alarming increase of drug resistance in human pathogens. The identification of new targets of known drugs is a promising approach, which has proven successful in several cases. Here, we describe a database that includes information on 5153 putative drug-target pairs for 150 human pathogens derived from available drug-target crystallographic complexes.