In Silico discovery of transcription factors as potential diagnostic biomarkers of ovarian cancer.
- Citation data:
BMC systems biology, ISSN: 1752-0509, Vol: 5, Issue: 1, Page: 144
- Publication Year:
- Vladimir Bajic
- Repository URL:
- PMC3184078; 3184078
- Biochemistry, Genetics and Molecular Biology; Mathematics; Computer Science; diagnostic agent; estrogen; transcription factor; tumor marker; binding site; biology; drug effect; evaluation; gene expression regulation; genetics; metabolism; methodology; ovary tumor; physiology; promoter region; tumor gene; Binding Sites; Computational Biology; Estrogens; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Ovarian Neoplasms; Promoter Regions, Genetic; Transcription Factors; Tumor Markers, Biological
Our study focuses on identifying potential biomarkers for diagnosis and early detection of ovarian cancer (OC) through the study of transcription regulation of genes affected by estrogen hormone.