Association of Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Autoantibodies With DRB1*07:01 and Severe Myositis in Juvenile Myositis Patients.

Citation data:

Arthritis care & research, ISSN: 2151-4658, Vol: 69, Issue: 7, Page: 1088-1094

Publication Year:
2017
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PMID:
28129483
DOI:
10.1002/acr.23113
Author(s):
Takayuki Kishi; Lisa G. Rider; Frederick W. Miller; Katherine Pak; Andrew L. Mammen; Lilliana Barillas-Arias; Michael Henrickson; Paul L. McCarthy; Bracha Shaham; Pamela F. Weiss; Iren Horkayne-Szakaly; Ira N. Targoff; Leslie S. Abramson; Daniel A. Albert; Alan N. Baer; Imelda M. Balboni; Susan Ballinger; Mara Becker; C. April Bingham; John F. Bohnsack; Gary R. Botstein; Ruy Carrasco; Victoria W. Cartwright; Chun Peng T. Chao; Randy Q. Cron; Rodolfo Curiel; Marietta M. DeGuzman; Wendy De la Pena; B. Anne Eberhard; Barbara S. Edelheit; Janet Ellsworth; Terri H. Finkel; Robert C. Fuhlbrigge; Christos A. Gabriel; Abraham Gedalia; Harry L. Gewanter; Ellen A. Goldmuntz; Donald P. Goldsmith; Beth S. Gottlieb; Brent Graham; Thomas A. Griffin; Hilary M. Haftel; William Hannan; Teresa Hennon; Mark F. Hoeltzel; J. Roger Hollister; Russell J. Hopp; Lisa F. Imundo; Anna Jansen; James Jarvis; Rita S. Jerath; Courtney R. Johnson; Olcay Y. Jones; Lawrence K. Jung; Ankur Kamdar; Ildy M. Katona; Hanna Kim; Susan Kim; Daniel J. Kingsbury; Steven J. Klein; Bianca A. Lang; Johanan Levine; Carol B. Lindsley; Gulnara Mamyrova; Ray Mitchell; Chihiro Morishima; David W. Moser; Frederick T. Murphy; Linda K. Myers; Kabita Nanda; Simona Nativ; Elif A. Oral; Barbara E. Ostrov; Ramesh Pappu; Christopher T. Parker; Murray H. Passo; Maria D. Perez; Donald A. Person; Marilyn G. Punaro; C. Egla Rabinovich; Robert M. Rennebohm; Rafael F. Rivas-Chacon; Tova Ronis; Margalit Rosenkranz; Adam Schiffenbauer; Robert M. Sheets; David D. Sherry; Edward M. Sills; Sara H. Sinal; Matthew Stoll; Sangeeta D. Sule; Robert P. Sundel; Richard K. Vehe; Scott A. Vogelgesang; Jennifer C. Wargula; Christine M. Yung; Lawrence S. Zemel Show More Hide
Publisher(s):
Wiley-Blackwell
Tags:
Medicine
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article description
Autoantibodies recognizing 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) are associated with statin exposure, the HLA allele DRB1*11:01, and necrotizing muscle biopsies in adult myositis patients. The aim of this study was to characterize the features of juvenile anti-HMGCR-positive myositis patients.