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Epidermal Growth Factor Inhibits Somatostatin-Induced Apoptosis

Journal of Surgical Research, ISSN: 0022-4804, Vol: 81, Issue: 1, Page: 95-100
1999
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Article Description

Background. The somatostatin analogue octreotide impairs intestinal regeneration and the adaptive response to intestinal resection by inhibition of enterocyte migration and proliferation and increased apoptosis. Epidermal growth factor (EGF) stimulates regeneration and adaptation by increasing proliferation and reducing apoptosis. The aim of this study was to determine the effect of EGF on octreotide-induced enterocyte apoptosis.

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