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New therapeutics to modulate mitochondrial dynamics and mitophagy in cardiac diseases

Journal of Molecular Medicine, ISSN: 1432-1440, Vol: 93, Issue: 3, Page: 279-287
2015
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Review Description

The processes that control the number and shape of the mitochondria (mitochondrial dynamics) and the removal of damaged mitochondria (mitophagy) have been the subject of intense research. Recent work indicates that these processes may contribute to the pathology associated with cardiac diseases. This review describes some of the key proteins that regulate these processes and their potential as therapeutic targets for cardiac diseases.

Bibliographic Details

Disatnik, Marie-Hélène; Hwang, Sunhee; Ferreira, Julio C B; Mochly-Rosen, Daria

Springer Science and Business Media LLC

Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics; Medicine

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