The assessment of macular electrophysiology and macular morphology in patients with vitiligo
International Ophthalmology, ISSN: 1573-2630, Vol: 38, Issue: 1, Page: 233-239
2018
- 7Citations
- 4Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations7
- Citation Indexes7
- CrossRef3
- Captures4
- Readers4
Article Description
Purpose: We aimed to analyze the electrophysiologic function and morphology of macula in vitiligo patients. Methods: Seventeen patients with vitiligo and 11 healthy subjects were studied. All participants underwent multifocal electroretinography (mfERG) and spectral domain optical coherence tomography (SD-OCT) evaluations. The mfERG (P1 mfERG responses central and peripheral) and retinal layer segmentation parameters (nine ETDRS subfields) were compared in vitiligo and control groups. Results: The mean P1 response amplitudes were significantly decreased in central and peripheral rings of the fovea in patients with vitiligo compared with controls (p = 0.002 and p = 0.006, respectively). There was a tendency toward a prolonged mean implicit time for both central and peripheral in patients with vitiligo compared to controls, however, with no statistical significance (p = 0.453 and p = 0.05, respectively). There was no statistically significant difference in all retinal layers thickness between two groups. Conclusion: In patients with vitiligo, while photoreceptor segment preserved in SD-OCT, mfERG reduced showing potential decline in central retinal function. This study showed a potential decline in central retinal function in patients with vitiligo even if they have normal fundus appearance and SD-OCT findings.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85009933447&origin=inward; http://dx.doi.org/10.1007/s10792-017-0452-3; http://www.ncbi.nlm.nih.gov/pubmed/28108905; http://link.springer.com/10.1007/s10792-017-0452-3; https://dx.doi.org/10.1007/s10792-017-0452-3; https://link.springer.com/article/10.1007/s10792-017-0452-3
Springer Science and Business Media LLC
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