Irritable bowel syndrome - Epidemiology and pathophysiology
Gastroenterologe, ISSN: 1861-9681, Vol: 8, Issue: 5, Page: 405-416
2013
- 3Citations
- 5Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Article Description
Irritable bowel syndrome (IBS) is one of the most frequent reasons why patients seek medical care and therefore, causes a significant socioeconomic burden. Historically, IBS is primarily a symptom-based diagnosis but such a symptom clustering causes significant problems because it is not clear whether and how IBS differs from other diseases. Recent findings indicate that IBS is associated with well-defined structural, molecular, genetic, immunological, neural and psychosocial abnormalities. The numerous pathophysiological mechanisms of IBS reflect the multifactorial character of this disease and strongly suggest the existence of pathophysiologically different disease entities. It is expected that further insight into the pathophysiological mechanisms and the association with clinical symptoms will improve the diagnostics and therapy of IBS in the future. The major challenge will be the development of biomarkers to characterize IBS subgroups to enable therapeutic strategies which target specific pathomechanisms. © 2013 Springer-Verlag Berlin Heidelberg.
Bibliographic Details
Springer Science and Business Media LLC
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