DNA: From Carrier of Genetic Information to Polymeric Materials
Transactions of Tianjin University, ISSN: 1995-8196, Vol: 25, Issue: 4, Page: 301-311
2019
- 4Citations
- 14Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Review Description
Research has shown that the DNA molecule can not only store genetic information but also serve as a polymeric biomolecule for the fabrication of functional materials. The unique precise molecular recognition capability and sequence programmability, combined with its good biocompatibility and biodegradability, impart the DNA molecule considerable potential for use in the construction of multifunctional materials. Depending on the composition, DNA-based materials have been generally categorized into pure DNA materials that are entirely composed of DNA and hybrid DNA materials that are composed of DNA and other functional compositions. Recently, we have developed a series of DNA-based materials that can be applied in diagnosis and therapy, and this review summarizes the relative work. Although challenges still exist regarding the real applications of DNA-based materials such as the high cost of DNA, the difficulty in scale-up, and the low resistance to nuclease, we believe that these drawbacks will be overcome with the development of technology, and new opportunities will emerge in the field of diagnosis and treatment.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85063002537&origin=inward; http://dx.doi.org/10.1007/s12209-019-00188-w; http://link.springer.com/10.1007/s12209-019-00188-w; http://link.springer.com/content/pdf/10.1007/s12209-019-00188-w.pdf; http://link.springer.com/article/10.1007/s12209-019-00188-w/fulltext.html; https://dx.doi.org/10.1007/s12209-019-00188-w; https://link.springer.com/article/10.1007/s12209-019-00188-w
Springer Science and Business Media LLC
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