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Highly distorted Cone calix[4]arenes through intramolecular mc murry coupling reaction

Tetrahedron, ISSN: 0040-4020, Vol: 51, Issue: 29, Page: 7951-7958
1995
  • 29
    Citations
  • 0
    Usage
  • 10
    Captures
  • 0
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Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    29
    • Citation Indexes
      29
  • Captures
    10

Article Description

Highly distorted and rigid cone conformers of calix[4]arene have been synthesized by low-valent titanium promoted intra -molecular coupling of aldehydes 1 a-d. The reaction outcome strongly depends on the substituents present at the upper rim and reaction time. In all cases examined infra-molecular coupled compounds, having a bridge only two atoms long, were obtained in about 30% yield.

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