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Synthesis of dinucleoside phosphorodithioates via thioamidites

Tetrahedron Letters, ISSN: 0040-4039, Vol: 29, Issue: 43, Page: 5517-5520
1988
  • 49
    Citations
  • 0
    Usage
  • 15
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    49
    • Citation Indexes
      49
  • Captures
    15

Article Description

Deoxynucleosides and S-(4-chlorobenzyl)-phosphorothiodiamidites react via phosphorothioamidites to form thiophosphite triesters. Sulfur oxidation yields dinucleoside phosphorodithioate triesters which can be used to selectively introduce dithioate linkages into DNA.

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