Functionalization of self-assembling peptides for neural tissue engineering
Self-assembling Biomaterials, Page: 475-493
2018
- 13Citations
- 23Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Book Chapter Description
It has become increasingly accepted that biomimetic bioabsorbable biomaterials are pivotal for improving neural tissue engineering. In this context, self-assembling peptides (SAPs) provide a versatile platform for multiple functionalizations targeting specific regenerative therapies. While the SAP synthesis process is suited for multiple functionalizations, the integration of functional motifs into SAPs needs to be carefully considered for not impairing self-assembly and ensuring proper exposure of functional motifs for optimal interactions with cells and tissues. Also, solubility and mechanical properties may be significantly altered. Data from molecular modeling, screening of functional motif libraries, in vitro tests and biomechanic studies can provide insightful information to design SAP scaffolds to promote functional nervous regeneration. Potential outcomes of this endeavor will be the setup of synthetic nervous organoids, of effective neural stem-cell carriers for transplants and feasible bioprostheses for the regeneration of nervous injuries.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/B978008102015900023X; http://dx.doi.org/10.1016/b978-0-08-102015-9.00023-x; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85061187222&origin=inward; https://linkinghub.elsevier.com/retrieve/pii/B978008102015900023X; https://dx.doi.org/10.1016/b978-0-08-102015-9.00023-x
Elsevier BV
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know