Ultrastructure of Trypanosoma cruzi and its interaction with host cells
American Trypanosomiasis Chagas Disease, Page: 401-427
2017
- 4Citations
- 56Captures
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Book Chapter Description
This review analyzes the fine structure of Trypanosoma cruzi as visualized by various morphological techniques, including scanning electron microscopy, transmission electron microscopy of thin sections and freeze-fracture replicas, and atomic force microscopy. Various structures, such as the glycocalyx, plasma membrane, flagellar pocket, cytoskeleton, flagellum, kinetoplast–mitochondrion complex, glycosome, acidocalcisome, lipid bodies, contractile vacuole, secretory pathway, endocytic pathway, and nucleus, are covered. We also review the structural aspects related with the binding of the infective trypomastigote and amastigote forms to the host cell surface, their recognition by surface-exposed ligands/receptors, triggering of the endocytic process, assembly of the parasitophorous vacuole (PV), interaction of this vacuole with the endolysosomal system, lysis of the PV membrane, and multiplication of amastigotes within the cell in direct contact with host cell organelles.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/B9780128010297000186; http://dx.doi.org/10.1016/b978-0-12-801029-7.00018-6; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85027189193&origin=inward; https://linkinghub.elsevier.com/retrieve/pii/B9780128010297000186; http://linkinghub.elsevier.com/retrieve/pii/B9780128010297000186; http://api.elsevier.com/content/article/PII:B9780128010297000186?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:B9780128010297000186?httpAccept=text/plain; https://dx.doi.org/10.1016/b978-0-12-801029-7.00018-6
Elsevier BV
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