Gold nanoparticles capped with sulfate-ended ligands as anti-HIV agents
Bioorganic & Medicinal Chemistry Letters, ISSN: 0960-894X, Vol: 20, Issue: 9, Page: 2718-2721
2010
- 143Citations
- 117Captures
Metric Options: Counts1 Year3 YearSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations143
- Citation Indexes143
- 143
- CrossRef123
- Captures117
- Readers117
- 117
Article Description
Gold nanoparticles coated with multiple copies of an amphiphilic sulfate-ended ligand are able to bind the HIV envelope glycoprotein gp120 as measured by surface plasmon resonance (SPR) and inhibit in vitro the HIV infection of T-cells at nanomolar concentrations. A 50% density of sulfated ligands on ∼2 nm nanoparticles (the other ligands being inert glucose derivatives) is enough to achieve high anti-HIV activities. This result opens up the possibility of tailoring both sulfated ligands and other anti-HIV molecules on the same gold cluster, thus contributing to the development of non-cocktail based multifunctional anti-HIV systems.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0960894X10004105; http://dx.doi.org/10.1016/j.bmcl.2010.03.079; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=77950858962&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/20382017; https://linkinghub.elsevier.com/retrieve/pii/S0960894X10004105; https://dx.doi.org/10.1016/j.bmcl.2010.03.079
Elsevier BV
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know