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First ex vivo validation of a radioguided surgery technique with β -radiation.

Physica Medica, ISSN: 1120-1797, Vol: 32, Issue: 9, Page: 1139-1144
2016
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Article Description

A radio-guided surgery technique with β- -emitting radio-tracers was suggested to overcome the effect of the large penetration of γ radiation. The feasibility studies in the case of brain tumors and abdominal neuro-endocrine tumors were based on simulations starting from PET images with several underlying assumptions. This paper reports, as proof-of-principle of this technique, an ex vivo test on a meningioma patient. This test allowed to validate the whole chain, from the evaluation of the SUV of the tumor, to the assumptions on the bio-distribution and the signal detection.

Bibliographic Details

E. Solfaroli Camillocci; R. Donnarumma; C. Mancini Terracciano; A. Russomando; G. Traini; R. Faccini; V. Bocci; G. Chiodi; F. Collamati; M. Marafini; S. Morganti; L. Recchia; M. Toppi; A. Carollo; M. Colandrea; C. M. Grana; M. Cremonesi; M. E. Ferrari; G. Pedroli; M. Schiariti; P. Ferroli; F. Ghielmetti; M. Patanè; B. Pollo

Elsevier BV

Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy

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