Repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex and cortical excitability in patients with major depressive disorder
Experimental Neurology, ISSN: 0014-4886, Vol: 196, Issue: 2, Page: 332-338
2005
- 45Citations
- 73Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations45
- Citation Indexes43
- 43
- CrossRef36
- Policy Citations2
- Policy Citation2
- Captures73
- Readers73
- 73
Article Description
Repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral prefrontal cortex is a relatively non-invasive technique with putative therapeutic effects in major depression. However, the exact neurophysiological basis of these effects needs further clarification. Therefore, we studied the impact of ten daily sessions of left, dorsolateral prefrontal rTMS on motor cortical excitability, as revealed by transcranial magnetic stimulation-elicited motor-evoked potentials in 30 patients. As compared to the non-responders, responders (33%) showed changes in parameters pointing towards a reduced cortical excitability. These results suggest that repetitive transcranial magnetic stimulation of the dorsolateral, prefrontal cortex may have inhibitory effects on motor cortical neuronal excitability in patients with major depressive disorder. Furthermore, measurement of motor cortical excitability may be a useful tool for investigating and monitoring inhibitory brain effects of antidepressant stimulation techniques like rTMS.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0014488605002839; http://dx.doi.org/10.1016/j.expneurol.2005.08.008; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=27744530194&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/16194530; https://linkinghub.elsevier.com/retrieve/pii/S0014488605002839; https://dx.doi.org/10.1016/j.expneurol.2005.08.008
Elsevier BV
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