Fracture non-union: Can biomarkers predict outcome?
Injury, ISSN: 0020-1383, Vol: 44, Issue: 12, Page: 1725-1732
2013
- 81Citations
- 101Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations81
- Citation Indexes78
- 78
- CrossRef55
- Policy Citations2
- Policy Citation2
- Patent Family Citations1
- Patent Families1
- Captures101
- Readers101
- 101
Review Description
Delayed bone healing and non-union occurs in approximately 10–15% of long bone fractures. Both pathologies may result in prolonged period of pain, disability and repetitive operative interventions. Despite intense investigations and progress done in understanding the pathophysiologic processes governing bone healing, the diagnostic tools have not been altered. The clinical findings and radiographic features remain the two important landmarks of diagnosing non-union and even when the diagnosis is established there is debate on the ideal timing and mode of intervention. Emerging evidence suggest that there are certain molecules and genes that can serve as predictors of potentially unsuccessful fracture union. This article summarises the current evidence on the available ‘bio-markers’to predict fracture non-union.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0020138313003975; http://dx.doi.org/10.1016/j.injury.2013.09.009; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84887086710&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/24075219; https://linkinghub.elsevier.com/retrieve/pii/S0020138313003975; http://www.injuryjournal.com/article/S0020-1383(13)00397-5/abstract; http://injuryjournal.com/retrieve/pii/S0020138313003975; http://www.injuryjournal.com/article/S0020138313003975/abstract; http://www.injuryjournal.com/article/S0020138313003975/fulltext; http://www.injuryjournal.com/article/S0020138313003975/pdf; http://linkinghub.elsevier.com/retrieve/pii/S0020138313003975; https://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?redirect=http%3A%2F%2Finjuryjournal.com%2Fretrieve%2Fpii%2FS0020138313003975&rc=0&code=jinj-site; http://acw.elsevier.com/SSOCore?return=https%3A%2F%2Fsecure.jbs.elsevierhealth.com%2Faction%2FconsumeSsoCookie%3FredirectUri%3Dhttp%253A%252F%252Finjuryjournal.com%252Faction%252FconsumeSharedSessionAction%253FJSESSIONID%253DaaaGxTEw2zcrL5dpEfVxv%2526MAID%253DcJiMHUR0sWP3gMEDSgfFmg%25253D%25253D%2526SERVER%253DWZ6myaEXBLGvmNGtLlDx7g%25253D%25253D%2526ORIGIN%253D465040555%2526RD%253DRD; http://acw.elsevier.com/SSOCore/?return=https%3A%2F%2Fsecure.jbs.elsevierhealth.com%2Faction%2FconsumeSsoCookie%3FredirectUri%3Dhttp%253A%252F%252Finjuryjournal.com%252Faction%252FconsumeSharedSessionAction%253FJSESSIONID%253DaaaGxTEw2zcrL5dpEfVxv%2526MAID%253DcJiMHUR0sWP3gMEDSgfFmg%25253D%25253D%2526SERVER%253DWZ6myaEXBLGvmNGtLlDx7g%25253D%25253D%2526ORIGIN%253D465040555%2526RD%253DRD; https://secure.jbs.elsevierhealth.com/action/consumeSsoCookie?redirectUri=http%3A%2F%2Finjuryjournal.com%2Faction%2FconsumeSharedSessionAction%3FJSESSIONID%3DaaaGxTEw2zcrL5dpEfVxv%26MAID%3DcJiMHUR0sWP3gMEDSgfFmg%253D%253D%26SERVER%3DWZ6myaEXBLGvmNGtLlDx7g%253D%253D%26ORIGIN%3D465040555%26RD%3DRD&acw=&utt=
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