Quinoline and 2-nitroimino-1, 3-diazacycloalkane hybrids: Design, synthesis and insecticidal activity
Journal of the Indian Chemical Society, ISSN: 0019-4522, Vol: 99, Issue: 1, Page: 100279
2022
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Article Description
A library of new hybrid molecules comprising quinoline, 2-nitroimino-1, 3-diazacycloalkane motifs were designed and synthesized as plausible neonicotinoid analogues. These compounds were synthesized from 2-chloro/aryloxy-3-formyl quinolines and guanidine nitrate with the coupling of 2-chloro/aryloxy-3-(chloromethyl)quinolines, 2-nitroimino-1, 3-diazacycloalkanes under phase transfer catalysis (PTC) as crucial step. All the compounds were obtained in excellent yields (80–90%) and were characterized by 1 H, 13 C NMR and mass spectrometry. The newly generated compounds were screened for insecticidal activity against aphids in safflower field and some of them displayed moderate activity.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S001945222100279X; http://dx.doi.org/10.1016/j.jics.2021.100279; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85120631211&origin=inward; https://linkinghub.elsevier.com/retrieve/pii/S001945222100279X; https://dx.doi.org/10.1016/j.jics.2021.100279
Elsevier BV
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