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GSPE is superior to NAC in the prevention of contrast-induced nephropathy: Might this superiority be related to caspase 1 and calpain 1?

Life Sciences, ISSN: 0024-3205, Vol: 103, Issue: 2, Page: 101-110
2014
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Article Description

Our study was intended to evaluate the role of inducible nitric oxide synthase (iNOS), endothelial nitric oxide synthase (eNOS), caspases 1 and 3 and calpain 1 in the pathogenesis of contrast-induced nephropathy (CIN) and to compare the protective effects of N acetyl cysteine (NAC) and grape seed proanthocyanidin extract (GSPE) against the development of CIN.

Bibliographic Details

Ulusoy, Sukru; Ozkan, Gulsum; Mungan, Sevdegül; Orem, Asım; Yulug, Esin; Alkanat, Mehmet; Yucesan, Fulya Balaban

Elsevier BV

Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics

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