Gene expression in Kinetoplastids
Current Opinion in Microbiology, ISSN: 1369-5274, Vol: 32, Page: 46-51
2016
- 121Citations
- 239Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations121
- Citation Indexes121
- 121
- CrossRef116
- Captures239
- Readers239
- 239
Review Description
Kinetoplastid parasites adapt to different environments with wide-reaching control of gene expression, but transcription of nuclear protein-coding genes is polycistronic: there is no individual control of transcription initiation. Mature mRNAs are made by co-transcriptional trans splicing and polyadenylation, and competition between processing and nuclear degradation may contribute to regulation of mRNA levels. In the cytosol both the extent to which mRNAs are translated, and mRNA decay rates, vary enormously. I here highlight gaps in our knowledge: no measurements of transcription initiation or elongation rates; no measurements of how, precisely, mRNA processing and nuclear degradation control mRNA levels; and extremely limited understanding of the contributions of different translation initiation factors and RNA-binding proteins to mRNA fate.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S1369527416300534; http://dx.doi.org/10.1016/j.mib.2016.04.018; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84966280550&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/27177350; https://linkinghub.elsevier.com/retrieve/pii/S1369527416300534; https://dx.doi.org/10.1016/j.mib.2016.04.018
Elsevier BV
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