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Maitake D-Fraction enhances antitumor effects and reduces immunosuppression by mitomycin-C in tumor-bearing mice

Nutrition, ISSN: 0899-9007, Vol: 21, Issue: 5, Page: 624-629
2005
  • 71
    Citations
  • 0
    Usage
  • 24
    Captures
  • 0
    Mentions
  • 20
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    71
  • Captures
    24
  • Social Media
    20
    • Shares, Likes & Comments
      20
      • Facebook
        20

Article Description

D-Fraction, a polysaccharide extracted from maitake mushrooms ( Grifola frondosa ), has been reported to exhibit an antitumor effect through activation of immunocompetent cells, including macrophages and T cells, with modulation of the balance between T-helper 1 and 2 cells. We examined whether D-Fraction could decrease the effective dosage of the chemotherapeutic agent, mitomycin-C (MMC), necessary to control carcinoma in mice.

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