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Vector control and entomological capacity for onchocerciasis elimination

Trends in Parasitology, ISSN: 1471-4922, Vol: 38, Issue: 7, Page: 591-604
2022
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Metric Options:   Counts1 Year3 Year

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Most Recent News

Lutte contre l'onchocercose : les piqûres de mouches noires sont considérablement réduites après la destruction des sites de reproduction

L'onchocercose, communément appelée cécité des rivières, est une maladie tropicale négligée qui provoque de graves démangeaisons, des affections cutanées défigurantes et des déficiences visuelles. Elle

Review Description

Mass drug administration (MDA) of ivermectin is currently the main strategy to achieve elimination of transmission (EoT) of onchocerciasis. Modelling suggests that EoT may not be reached in all endemic foci using annual MDA alone. Onchocerciasis and loiasis are coendemic in forest areas of Central Africa where ivermectin treatment can lead to severe adverse events in individuals with heavy loiasis load, rendering MDA inappropriate. Vector control has been proposed as a complementary intervention strategy. Here, we discuss (i) achievements and pitfalls of previous interventions; (ii) epidemiological impact, feasibility, and combination with MDA to accelerate and/or protect EoT; (iii) role of modelling; (iv) opportunities for innovative methods of vector monitoring and control; and (v) strengthening entomological capacity in endemic countries.

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