PlumX Metrics
Embed PlumX Metrics

Gene Regulation and Speciation

Trends in Genetics, ISSN: 0168-9525, Vol: 33, Issue: 1, Page: 68-80
2017
  • 119
    Citations
  • 0
    Usage
  • 313
    Captures
  • 2
    Mentions
  • 12
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    119
  • Captures
    313
  • Mentions
    2
    • Blog Mentions
      1
      • Blog
        1
    • News Mentions
      1
      • News
        1
  • Social Media
    12
    • Shares, Likes & Comments
      12
      • Facebook
        12

Most Recent News

A lethal mitonuclear incompatibility in complex I of natural hybrids

Nature, Published online: 10 January 2024; doi:10.1038/s41586-023-06895-8 Analysis of naturally hybridizing swordtail fish species reveals a mitonuclear genetic incompatibility among three genes that encode components of mitochondrial respiratory complex I, providing insights into the emergence of hybrid incompatibilities and reproductive barriers.

Review Description

Understanding the genetic architecture of speciation is a major goal in evolutionary biology. Hybrid dysfunction is thought to arise most commonly through negative interactions between alleles at two or more loci. Divergence between interacting regulatory elements that affect gene expression (i.e., regulatory divergence) may be a common route for these negative interactions to arise. We review here how regulatory divergence between species can result in hybrid dysfunction, including recent theoretical support for this model. We then discuss the empirical evidence for regulatory divergence between species and evaluate evidence for misregulation as a source of hybrid dysfunction. Finally, we review unresolved questions in gene regulation as it pertains to speciation and point to areas that could benefit from future research.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know