Analysis of archived newborn dried blood spots (DBS) identifies congenital cytomegalovirus as a major cause of unexplained pediatric sensorineural hearing loss.

Citation data:

American journal of otolaryngology, ISSN: 1532-818X, Vol: 38, Issue: 5, Page: 565-570

Publication Year:
2017
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PMID:
28629849
DOI:
10.1016/j.amjoto.2017.06.002
Author(s):
Meyer, Lucy, Sharon, Bazak, Huang, Tina C, Meyer, Abby C, Gravel, Kristin E, Schimmenti, Lisa A, Swanson, Elizabeth C, Herd, Hannah E, Hernandez-Alvarado, Nelmary, Coverstone, Kirsten R, McCann, Mark, Schleiss, Mark R Show More Hide
Publisher(s):
Elsevier BV
Tags:
Medicine
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article description
Congenital cytomegalovirus (cCMV) infection is the most common non-genetic cause of sensorineural hearing loss (SNHL). However, accurate diagnosis of cCMV as the etiology of SNHL is problematic beyond the neonatal period. This study therefore examined whether cCMV infection could be identified retrospectively in children presenting with unexplained SNHL to a multidisciplinary diagnostic outpatient otolaryngology clinic at an academic medical center in Minnesota.

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