Central venous catheter-related infections caused by Corynebacterium amycolatum and other multiresistant non-diphtherial corynebacteria in paediatric oncology patients.

Citation data:

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, ISSN: 1678-4391, Vol: 22, Issue: 4, Page: 347-351

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Carvalho, Ricardo Vianna de; Lima, Fernanda Ferreira da Silva; Santos, Cíntia Silva Dos; Souza, Mônica Cristina de; Silva, Rondinele Santos da; Mattos-Guaraldi, Ana Luiza de
Elsevier BV; Brazilian Society of Infectious Diseases
article description
Bloodstream and venous catheter-related corynebacterial infections in paediatric patients with haematological cancer were investigated from January 2003 to December 2014 at the Brazilian National Cancer Institute in Rio de Janeiro, Brazil. We observed that during cancer treatment, invasive corynebacterial infections occurred independent of certain factors, such as age and gender, underlying diseases and neutropenia. These infections were ssscaused by Corynebacterium amycolatum and other non-diphtherial corynebacteria. All cases presented a variable profile of susceptibility to antimicrobial agents, except to vancomycin. Targeted antibiotic therapy may contribute to catheters maintenance and support quality of treatment. Non-diphtherial corynebacteria must be recognized as agents associated with venous access infections. Our data highlight the need for the accurate identification of corynebacteria species, as well as antimicrobial susceptibility testing.