Inadequate use of antibiotics and increase in neonatal sepsis caused by resistant bacteria related to health care assistance: a systematic review.

Citation data:

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, ISSN: 1678-4391, Vol: 22, Issue: 4, Page: 328-337

Publication Year:
2018
Captures 12
Readers 12
PMID:
30125532
DOI:
10.1016/j.bjid.2018.07.009
Author(s):
Silva, Ana Carolina Bueno; Anchieta, Leni Marcia; Lopes, Marianna Fischer de Paula; Romanelli, Roberta Maia de Castro
Publisher(s):
Elsevier BV; Brazilian Society of Infectious Diseases
Tags:
Medicine
review description
Technologies and life support management have enhanced the survival of preterm infants. The immune system of newborns is immature, which contributes to the occurrence of healthcare-associated infections. The overlap of several conditions with neonatal sepsis and the difficulty of diagnosis and laboratory confirmation during this period result in a tendency to over-treat neonatal sepsis. The use of antimicrobial agents is a risk factor for multidrug-resistant bacterial infections. This work aimed to perform a systematic review of the relationship between inadequate use of antimicrobial agents and increase in neonatal sepsis related to healthcare assistance, due to bacterial resistance.