Applicability of an instrument to identify human leukocyte antigen-compatible donors for platelet transfusions.

Citation data:

Hematology, transfusion and cell therapy, ISSN: 2531-1387, Vol: 40, Issue: 4, Page: 298-304

Publication Year:
2018
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PMID:
30370406
DOI:
10.1016/j.htct.2018.03.004
Author(s):
Ferreira, Millena Gomes; De Vito, Fernanda Bernadelli; Ferreira, Aline Aparecida; Bub, Carolina Bonet; Santos, Fernando Antônio Vinhal Dos; Filho, Adilson Botelho; Silva, Sheila Soares; Moraes-Souza, Helio
Publisher(s):
Elsevier BV; Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular (ABHH)
Tags:
Medicine
article description
The selection of compatible human leukocyte antigen platelets has been associated with improved platelet increments. Therefore, an effective strategy would be the selection of donors who are genetically compatible according to the human leukocyte antigen system. Nonetheless, this is costly as it concerns a highly polymorphic system, which requires a large bank of genotyped donors.