Estimulación cerebral profunda en pacientes parkinsonianos con intolerancia a levodopa.

Citation data:

Neurocirugia (Asturias, Spain), ISSN: 2340-6305, Vol: 29, Issue: 4, Page: 213-215

Publication Year:
2018
Captures 4
Readers 4
PMID:
29089239
DOI:
10.1016/j.neucir.2017.09.005
Author(s):
García-Ruiz, Pedro J; Feliz-Feliz, Cici; Ayerbe Gracia, Joaquín; Matías Arbelo, José; Salvador, Carlos; Val Fernández, Javier Del; García-Caldentey, Juan
Publisher(s):
Elsevier BV
Tags:
Medicine
article description
Deep brain stimulation (DBS) is at present, a useful treatment for patients with advanced Parkinson's disease and motor complications. The crucial step toward consistent DBS outcomes remains careful patient selection; several conditions must be fulfilled including excellent levo dopa response. We report two cases of early onset Parkinson's disease with severe intolerance to levo dopa but excellent and sustained response to DBS. DBS can be a useful alternative for parkinsonian patients with severe intolerance to levo dopa, provided a positive acute response to levo dopa or apomorphine is obtained.