Maintenance of genetic homogeneity in systems with multiple genomes
Genetical Research, ISSN: 1469-5073, Vol: 27, Issue: 2, Page: 249-265
1976
- 48Citations
- 10Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations48
- Citation Indexes48
- CrossRef48
- 42
- Captures10
- Readers10
- 10
Article Description
Genes or sequences of DNA present in multiple copies per cell include entire genomes of mitochondria and chloroplasts, nuclear ribosomal RNA genes, and highly repetitive sequences in heterochromatin. All copies are nearly identical, in spite of mutational pressure and weak selection. A zygote containing mitochondrial or chloroplast genophores of two different genotypes quickly produces progeny pure for one genotype or another (vegetative segregation). Evidence from yeast and Chlamy-domonas suggests that organelle genophores undergo repeated rounds of random mating and recombination. When two molecules carrying different alleles at a locus recombine, gene conversion can result in the cell becoming pure for one allele. Stochastic matching and conversion (SMAC) has been studied by computer simulations which suggest that it will tend to eliminate new mutations in yeast mitochondrial DNA and speed up vegetative segregation. We have verified previous suggestions that gene conversion, occurring during unequal mitotic sister-strand crossing-over, provides an efficient mechanism for maintaining the homogeneity of repeated sequences in eukaryotic chromosomes. © 1976, Cambridge University Press. All rights reserved.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0017143268&origin=inward; http://dx.doi.org/10.1017/s001667230001644x; http://www.ncbi.nlm.nih.gov/pubmed/1278687; https://www.cambridge.org/core/product/identifier/S001667230001644X/type/journal_article; http://www.journals.cambridge.org/abstract_S001667230001644X; https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S001667230001644X
Hindawi Limited
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