John S. Fossey is British chemist. He is a professor of synthetic chemistry at the University of Birmingham in the United Kingdom, and a visiting professor at Henan Normal University and guest professor at East China University of Science and Technology, both in China. His res...
Asymmetric Synthesis of cis-3,4-Dihydrocoumarins via [4 + 2] Cycloadditions Catalyzed by Amidine Derivatives.
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The Journal of organic chemistry, ISSN: 1520-6904, Vol: 82, Issue: 10, Page: 5424-5432
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A highly efficient chiral amidine derivative-catalyzed tandem Michael addition/lactonization of carboxylic acids and o-quinone methides (o-QMs) has been developed that enables the asymmetric synthesis of cis-3,4-dihydrocoumarins bearing contiguous tertiary stereogenic centers in high yields with excellent stereoselectivities.