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Synthesis of indole alkaloid analogues: Novel domino stereoselective electrophile addition - Cyclizations of tryptophan-derived α-amino nitriles

Journal of Organic Chemistry, ISSN: 0022-3263, Vol: 72, Issue: 14, Page: 5395-5398
2007
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(Chemical Equation Presented) The synthesis of new indole alkaloid analogues, containing a 1,2,4,5,10b,10c-hexahy dropyrrolo[1′,2′, 3′:1,9a,9]imidazo-[1,2-a]indole skeleton, via highly stereoselective novel domino cyclative halogenation or prenylation reactions of tryptophan-derived α-amino nitriles, is described. © 2007 American Chemical Society.

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