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Improved and expanded Q-system reagents for genetic manipulations

Nature Methods, ISSN: 1548-7105, Vol: 12, Issue: 3, Page: 219-222
2015
  • 134
    Citations
  • 0
    Usage
  • 258
    Captures
  • 2
    Mentions
  • 15
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    134
  • Captures
    258
  • Mentions
    2
    • Blog Mentions
      1
      • Blog
        1
    • References
      1
      • Wikipedia
        1
  • Social Media
    15
    • Shares, Likes & Comments
      15
      • Facebook
        15

Article Description

The Q system is a repressible binary expression system for transgenic manipulations in living organisms. Through protein engineering and in vivo functional tests, we report here variants of the Q-system transcriptional activator, including QF2, for driving strong and ubiquitous expression in all Drosophila tissues. Our QF2, Gal4QF and LexAQF chimeric transcriptional activators substantially enrich the toolkit available for transgenic regulation in Drosophila melanogaster.

Bibliographic Details

Riabinina, Olena; Luginbuhl, David; Marr, Elizabeth; Liu, Sha; Wu, Mark N; Luo, Liqun; Potter, Christopher J

Springer Science and Business Media LLC

Biochemistry, Genetics and Molecular Biology

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