Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections
RSC Advances, ISSN: 2046-2069, Vol: 13, Issue: 44, Page: 31059-31066
2023
- 3Citations
- 4Captures
- 1Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Data from University of Catania Advance Knowledge in Bacterial Infections and Mycoses (Curcumin I-sma Nanomicelles As Promising Therapeutic Tool To Tackle Bacterial Infections)
2024 MAR 21 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Drug Daily -- Current study results on Bacterial Infections and Mycoses have
Article Description
Renewed interest towards natural substances has been pushed by the widespread diffusion of antibiotic resistance. Curcumin I is the most active and effective constituent of curcuminoids extracted from Curcuma longa and, among other beneficial effects, attracted attention for its antimicrobial potential. Since the poor pharmacokinetic profile hinders its efficient utilization, in the present paper, we report encapsulation of curcumin I in poly(styrene-co-maleic acid) (SMA-CUR) providing a nanomicellar system with improved aqueous solubility and bioavailability. SMA-CUR was characterized by means of size, zeta potential, polydispersity index, atomic force microscopy (AFM), drug release studies, spectroscopic properties and stability. SMA-CUR nanoformulation displayed exciting antimicrobial properties compared to free curcumin I towards Gram-positive and Gram-negative clinical isolates.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85175349882&origin=inward; http://dx.doi.org/10.1039/d3ra04885c; http://www.ncbi.nlm.nih.gov/pubmed/37881762; https://xlink.rsc.org/?DOI=D3RA04885C; https://dx.doi.org/10.1039/d3ra04885c; https://pubs.rsc.org/en/content/articlelanding/2023/ra/d3ra04885c
Royal Society of Chemistry (RSC)
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