A practicable environmentally benign one-pot synthesis of 2-arylbenzofurans at room temperature
Green Chemistry, ISSN: 1463-9270, Vol: 14, Issue: 3, Page: 695-701
2012
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- 16Captures
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Article Description
An environmentallyfriendly one-pot synthesis of 2-arylbenzofurans under ambient temperature has been developed. It features an ortho-hydroxyl group assisted Wittig reaction of substituted salicylaldehyde followed by an in situ oxidative cyclization. Its advantages include readily available and non-hazardous materials, benign reaction conditions (room temperature, green solvent and one-pot manner), easy work-up and high overall yields. Utilizing this methodology, various 2-aryl-benzofurans including four natural products have been synthesized. © 2012 The Royal Society of Chemistry.
Bibliographic Details
Royal Society of Chemistry (RSC)
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