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Au nanoparticles deposited on ultrathin two-dimensional covalent organic framework nanosheets for: In vitro and intracellular sensing

Nanoscale, ISSN: 2040-3372, Vol: 12, Issue: 14, Page: 7776-7781
2020
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Covalent Organic Framework-Based Theranostic Platforms for Restricting H1N1 Influenza Virus Infection

Introduction The influenza virus outbreak causes severe respiratory system infection and enormous challenges to public health.1–3 History has proved that influenza viruses spread will result

Article Description

A novel composite nanomaterial is prepared by growing small Au nanoparticles on two-dimensional covalent organic framework nanosheets (Au NPs/COF NSs). The synthesized hybrid nanosheets are used as a new platform for multiplexed detection of hepatitis A virus DNA (HAV) and hepatitis B virus DNA (HBV). Additionally, this sensing platform based on Au NPs/COF NSs can be used as a candidate for monitoring the distribution of potassium ions (K) and the intracellular K level in living cells. Accordingly, the sensing systems based on hybrid Au NPs/COF NSs have shown great potential for the investigation of biomolecules and related biological applications.

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