A comparison of several algorithms for the single individual SNP haplotyping reconstruction problem
Bioinformatics, ISSN: 1367-4803, Vol: 26, Issue: 18, Page: 2217-2225
2010
- 57Citations
- 77Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations57
- Citation Indexes57
- CrossRef57
- 57
- Captures77
- Readers77
- 77
Review Description
Motivation: Single nucleotide polymorphisms are the most common form of variation in human DNA, and are involved in many research fields, from molecular biology to medical therapy. The technological opportunity to deal with long DNA sequences using shotgun sequencing has raised the problem of fragment recombination. In this regard, Single Individual Haplotyping (SIH) problem has received considerable attention over the past few years. Results: In this article, we survey seven recent approaches to the SIH problem and evaluate them extensively using real human haplotype data from the HapMap project. We also implemented a data generator tailored to the current shotgun sequencing technology that uses haplotypes from the HapMap project. © The Author(s) 2010. Published by Oxford University Press.
Bibliographic Details
Oxford University Press (OUP)
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