Modulation of the neurotransmitter release in rat cerebellar neurons by GROβ
NeuroReport, ISSN: 0959-4965, Vol: 9, Issue: 16, Page: 3601-3606
1998
- 72Citations
- 6Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations72
- Citation Indexes72
- 72
- CrossRef63
- Captures6
- Readers6
Article Description
We report here that, in cultured cerebellar granule cells, the CXC chemokine GROβ stimulates the signaling pathway of the extracellular signal- regulated kinases, and enhances both evoked and spontaneous postsynaptic currents in patch clamped Purkinje neurons from rat cerebellar slices. The GROβ-induced enhancement of the excitatory post-synaptic currents evoked by stimulating the parallel fibres is blocked by the inhibitor of the extracellular signal-regulated kinases pathway PD98059, which also reduces both basal frequency of spontaneous post-synaptic currents and mean amplitude of evoked excitatory post-synaptic currents. Our results suggest that GROβ modulates neurotransmitter release in the cerebellum through the activation of the extracellular signal-regulated kinases pathway.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0032538957&origin=inward; http://dx.doi.org/10.1097/00001756-199811160-00011; http://www.ncbi.nlm.nih.gov/pubmed/9858367; http://journals.lww.com/00001756-199811160-00011; https://dx.doi.org/10.1097/00001756-199811160-00011; https://insights.ovid.com/article/00001756-199811160-00011
Ovid Technologies (Wolters Kluwer Health)
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