Five years of steroid sparing in renal transplantation with tacrolimus and mycophenolate mofetil
Transplantation, ISSN: 0041-1337, Vol: 81, Issue: 1, Page: 125-128
2006
- 24Citations
- 14Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations24
- Citation Indexes24
- 24
- CrossRef20
- Captures14
- Readers14
- 14
Article Description
Steroid sparing with tacrolimus and mycophenolate mofetil (MMF) is associated with good short-term renal transplant outcomes. However, late allograft dysfunction and failure remain concerns. In this study, 101 consecutive patients underwent renal transplantation with tacrolimus, MMF, and 7 days of corticosteroids only. After a median follow-up of 51 months (range 36-62), overall patient survival is 97%, and overall survival with graft function is 91%. The acute rejection rate at 12 months was 19%. Late rejection was uncommon, with only three further episodes beyond 12 months. Graft function was stable during the study, with a mean creatinine of 140 μmol/L and mean estimated creatinine clearance of 57 ml/min at the end of follow-up. Six patients developed posttransplant diabetes mellitus (three cases beyond 12 months). This steroid avoidance regimen is associated with excellent medium-term patient and graft outcomes, and a low incidence of side effects. Copyright © 2006 by Lippincott Williams & Wilkins.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=31044449097&origin=inward; http://dx.doi.org/10.1097/01.tp.0000189716.50701.2d; http://www.ncbi.nlm.nih.gov/pubmed/16421488; https://journals.lww.com/00007890-200601150-00022; https://dx.doi.org/10.1097/01.tp.0000189716.50701.2d; https://journals.lww.com/transplantjournal/Fulltext/2006/01150/Five_Years_of_Steroid_Sparing_in_Renal.22.aspx
Ovid Technologies (Wolters Kluwer Health)
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