500-Gray γ-Irradiation May Increase Adhesion Strength of Lyophilized Cadaveric Split-Thickness Skin Graft to Wound Bed.

Citation data:

Annals of plastic surgery, ISSN: 1536-3708, Vol: 78, Issue: 3 Suppl 2, Page: S135-S138

Publication Year:
2017
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PMID:
00000637-201703002-00020, 28166140, 00000637-900000000-97808
DOI:
10.1097/sap.0000000000001019
Author(s):
Wei, Lin-Gwei, Chen, Chieh-Feng, Wang, Chi-Hsien, Cheng, Ya-Chen, Li, Chun-Chang, Chiu, Wen-Kuan, Wang, Hsian-Jenn
Publisher(s):
Ovid Technologies (Wolters Kluwer Health)
Tags:
Medicine
article description
Human cadaveric skin grafts are considered as the "gold standard" for temporary wound coverage because they provide a more conductive environment for natural wound healing. Lyophilization, packing, and terminal sterilization with gamma-ray can facilitate the application of cadaveric split-thickness skin grafts, but may alter the adhesion properties of the grafts. In a pilot study, we found that 500 Gy γ-irradiation seemed not to reduce the adherence between the grafts and wound beds.

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