Limited role of differential fractionation in genome content variation and function in maize (Zea mays L.) inbred lines.

Citation data:

The Plant journal : for cell and molecular biology, ISSN: 1365-313X, Vol: 93, Issue: 1, Page: 131-141

Publication Year:
2017
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PMID:
29124819
DOI:
10.1111/tpj.13765
Author(s):
Alex B. Brohammer, Thomas J. Y. Kono, Nathan M. Springer, Suzanne E. McGaugh, Candice N. Hirsch
Publisher(s):
Wiley-Blackwell
Tags:
Biochemistry, Genetics and Molecular Biology, Agricultural and Biological Sciences
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article description
Maize is a diverse paleotetraploid species with considerable presence/absence variation and copy number variation. One mechanism through which presence/absence variation can arise is differential fractionation. Fractionation refers to the loss of duplicate gene pairs from one of the maize subgenomes during diploidization. Differential fractionation refers to non-shared gene loss events between individuals following a whole genome duplication event. We investigated the prevalence of presence/absence variation resulting from differential fractionation in the syntenic portion of the genome using two whole genome de novo assemblies of the inbred lines B73 and PH207. Between these two genomes, syntenic genes were highly conserved with less than 1% of syntenic genes being subject to differential fractionation. The few variably fractionated syntenic genes that were identified are unlikely to contribute to functional phenotypic variation, as there is a significant depletion of these genes in annotated gene sets. In further comparisons of 60 diverse inbred lines, non-syntenic genes were six times more likely to be variable compared to syntenic genes, suggesting that comparisons among additional genome assemblies are not likely to result in the discovery of large-scale presence/absence variation among syntenic genes. This article is protected by copyright. All rights reserved.

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